FARNESOID X RECEPTOR VIA NOTCH1 DIRECTS ASYMMETRIC CELL DIVISION OF SOX9+ CELLS TO PREVENT THE DEVELOPMENT OF LIVER CANCER IN A MOUSE MODEL

Farnesoid X receptor via Notch1 directs asymmetric cell division of Sox9+ cells to prevent the development of liver cancer in a mouse model

Abstract Background Asymmetrical cell division (ACD) maintains the proper Soft Toy number of stem cells to ensure self-renewal.The rate of symmetric division increases as more cancer stem cells (CSCs) become malignant; however, the signaling pathway network involved in CSC division remains elusive.FXR (Farnesoid X receptor), a ligand-activated tran

read more

Perspektif Hukum dalam Main Hakim Sendiri

Pengeroyokan yang terjadi di masyarakat akhir-akhir ini sering diberitakan baik dalam media cetak maupun televisi.Maling yang dihajar hingga babak belur, pemerkosa yang dianiaya keluarga korban, bahkan yang lebih miris yaitu kejadian pembakaran oleh warga terhadap orang-orang yang diduga sebagai dukun santet.Tidak dapat dipungkiri selain di kota-ko

read more

Assessing the Impact of Surface and Upper-Air Observations on the Forecast Skill of the ACCESS Numerical Weather Prediction Model over Australia

The impact of the Australian Bureau of Meteorology’s in situ observations (land and sea surface observations, upper air observations by radiosondes, pilot balloons, wind profilers, and aircraft observations) on the short-term forecast skill provided by the ACCESS (Australian Community Climate and Earth-System Simulator) global numerical weather p

read more